A lot could be said about this chapter! Robert Gagnon has probably said it already. Here I offer three observations:
(1) The whole chapter is important, not simply one or two verses. It is worth asking, what is the whole chapter about, and how do the individual proscriptions within it relate to the chapter as a whole?
(2) In respect of the topic of 'the Bible and homosexuality', 18:22 is very important. It is the key Old Testament text underlying the New Testament texts which are normally discussed within that topic (i.e. Romans 1:18-32; 1 Corinthians 6:9-10; 1 Timothy 1:10). One reason for saying this is that in the Greek Old Testament, Leviticus 18:22, reads, "καὶ μετὰ ἄρσενος οὐ κοιμηθήσῃ κοίτην γυναικός· βδέλυγμα γάρ ἐστιν" so that the words for 'man' (arsenos) and for 'bed' (koiten) appear to be conjoined together in 1 Corinthians 6:9 and 1 Timothy 1:10 which both use arsenokoitai. (1 Corinthians 6:9 may in fact be the earliest use of this compound word, raising the question of whether it is directly conjoined from the Greek Old Testament).
(3) Leviticus is, quite obviously, part of the Law of Moses. Jesus had quite a bit to say about the Law of Moses. Any observations about Jesus' silence regarding homosexuality should engage with what Jesus had to say about the Law of Moses. On that topic, Jesus was not silent!